I'm using VueScan Pro to scan and save as TIFF files. When VueScan saves them the filesize is around 50Mb for a 35mm colour negative. But when I open it in PE14 and refine the image when I save it as a TIFF the file size doubles or trebles to 100-150Mb. Seems there's no difference whether compression is used or not. How can I reduce the size of these TIFF files?