It all depends what sort of integrity you wish to retain in your non-news, non-natural history photographs*. And also whether you wish to use any software manipulation at all. There are, or at least were a couple of seasons back, a significant proportion of members in some camera clubs who are or were extremely hostile to post-production manipulation. Or, you may wish to go totally the other way and only ever produce 'constructivist' images, taking out most of one or more 'captures' to compile a creation. Beware though, the word going round at present is that the constructivists may 'have had their day'. I have to admit that I would flatter some portrait sitters at times by using some soft focus, usually at the print making stage, with film. So why not with digital? Similarly, I would burn in a sky or corners or foreground or dodge parts of a print during exposure or retouch tiny light areas as well as spots or lines if intrusive or spoiling the effect that I want. Again, why not with digital? * For those who may not know there are rules/conventions concerning post-production removal in these genres and breaking them may have very severe consequences.